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They used different concentrations of ARA-290 or a control solution on the murine models' hind appendages

In line with our results, some studies have shown that chronic alcohol impairs long-term memory but not short-term memory in adolescent mice, or that acute alcohol exposure disrupts memory acquisition but not consolidation [45,46,47]

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This often relates to reduced caloric intake as appetite drops

In an in-vivo study, it has been seen that mitochondrial ROS can have less detrimental effects in worms by increasing their lifespan while increased level of ROS in cytoplasmic may have less lifespan of worms [43]

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