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The mechanisms by which incretin-based therapies exert these effects include signals in the central nervous system to suppress appetite, increase satiety, and thereby decrease calorie intake, improvements in insulin sensitivity, and many other extrahepatic effects [91]

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Many symptoms of MCAS overlap with Lyme disease, and effectively treating MCAS not only helps the patient feel better, but it also helps to clarify what symptoms remain from Lyme disease

Depression is a disorder characterized by a loss of interest in daily activities, fatigue, low mood, and cognitive symptoms that impair daily functioning [3]