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Transcriptomic studies of cerebrovascular smooth muscle cells treated with sHE inhibitor in DM-ADRD rat models revealed significant enrichment of the cell contractile pathways, as identified by KEGG analysis [208]

In this context, interest has emerged in incretin receptor agonists as potential modulators of pulmonary fibrotic pathways, although the supporting evidence remains preliminary

However, the limited sample size of their study (only 20 patients) may have limited the generalizability of the results, and they failed to investigate the specific receptor-mediated mechanism underlying the effect of SSRIs on tubal motility and the fallopian tubes at different stages of the menstrual cycle

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retinopathy and foot disease), together with a timely referral to a nephrology service, are important considerations in the optimal care of people with DKD