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Additionally, they inhibit the function of macrophages in the blood vessels and production of pro-inflammatory cytokines such as IL-6, IL-1, TNF-, and C-reactive protein (CRP)

This breakthrough offers new hope for millions of patients struggling with diabetes-related kidney complications, providing a more effective treatment option to improve long-term health outcomes

Glutathione is a naturally occurring antioxidant produced in the liver

Then came ACHIEVE-3 , published in The Lancet in February 2026, the first direct head-to-head comparison between two oral GLP-1 therapies

The additional GIP activation enhances fat metabolism and may provide greater weight loss compared to GLP-1 agonists alone