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In one double-blind insomnia study involving 16 patients, DSIP modestly improved sleep efficiency and time-to-fall-asleep over 3 nights of intravenous use, but the effects were described as weak and have not been confirmed in large modern trials

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Facile preparation of pna-peptide conjugates with a polar maleimide-thioether linkage

10.1016/j.dsx.2023.102834 80 NakamuraK.RadhakrishnanK.WongY

Women of childbearing potential should use effective contraception during treatment, and semaglutide should be discontinued at least 2 months before a planned pregnancy