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Semaglutide showed a lower risk of the secondary composite endpoint of heart failure hospitalization or urgent heart failure visit compared to sitagliptin in the expanded populations (HR 0.61, 95% CI 0.57 to 0.66)

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Two groups were matched for age, gender, comorbidities, and other soft tissue and inflammatory issues, HbA1c, sleep apne, BMI, opioid use, NSAID use, antidepressants

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