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SB-01 is a synthetic 7-amino-acid peptide in clinical trials that downregulates TGF-beta-1, a growth factor highly expressed in degenerated discs

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(7) Particularly in the case of continuous exposure for 24 hours, the peptide apparently led to an increase from roughly 2030 gL24 h under placebo conditions to about 120180 gL24 h with GHRP-2, implying an approximate 4- to 6-fold rise in growth hormone production

These are the largest weight-loss results ever recorded in a Phase 2 obesity trial

Alternative treatment approaches may be explored in selected cases

F., & Chang, C