They provide a steady release of hormones over time, which can be beneficial for those experiencing fluctuating symptoms
Summary: Excessive vitamin B12 intake rarely causes toxicity, but very high levels from supplements or injections may be associated with skin reactions such as acne-like eruptions, though serious adverse effects remain exceptionally uncommon
DOI: 10.1016/j.jpba.2021.114255 PMID: 34304009 5-AMQ
Patients with pre-existing conditions including cardiovascular disease, liver disease, thyroid disorders, kidney disease, or gallbladder disease face particular uncertainty
Neurological disorders caught early on can often be reversed
Motor : muscle weakness, ataxia, reduced reflexes (if peripheral neuropathy) or increased reflexes and/or upgoing plantars (if central neuropathy)