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The brain and central nervous system (CNS) are susceptible targets for attack by ROS and RNS, due to several factors: high concentrations of mitochondria, low levels of antioxidants, presence of polyunsaturated fatty acids (targets for oxidation) in the basal tissue, high rates of oxygen consumption, presence of iron-dependent metabolic pathways, and the generation of nitric oxide [1,2,3]
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Le TB-500 (a fragment of thymosin beta-4) primarily acts on cell migration and actin regulation
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