J Immunol 138 , 32133218 (1987)
And they have FIVE OTHER molecules I didnt mention in their development pipeline in phase 1 or 2 trials
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Wang et al., 2021b
Variants in JAK2, TYK2, STAT1, STAT3, STAT4 genes increase UC susceptibility [19], and JAK3 knockout mice develop severe combined immunodeficiency, affecting T and B cell development, resulting in IEC differentiation defects and impaired intestinal barrier function, thus increasing susceptibility to UC [131]
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