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[4] [5] These agents work by mimicking natural gut hormones that regulate appetite and blood glucose levels, slowing gastric emptying, enhancing satiety, and promoting weight reduction when combined with lifestyle modifications

Common Side Effects of Semaglutide Like any medication, semaglutide can cause side effects

Glucagon receptor activation is the novel addition

Metabolic rate decreases beyond what the lost weight alone would predict, a phenomenon called adaptive thermogenesis

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Activation of this receptor also slows gastric emptying, promotes satiety, and reduces food intake, contributing to weight management and appetite control