According to FDA prescribing information, the incidence varies depending on the formulation and dose
So, Are GLP-1s Ever a Good Option
Semaglutide: Can cause gastrointestinal side effects, especially at the beginning of the treatment, including nausea, and constipation and some may experience vomiting, and diarrhea in rare cases
Contact your GP immediately or call NHS 111 if you experience severe or persistent abdominal pain, particularly if it's sharp, localised, or worsening
Clinical trials extending to 3+ years show sustained safety and efficacy with no major unexpected adverse events
The Real Results of GLP-1 in 2025 Weight Loss Outcomes By 2025, clinical data and real-world use paint a clear picture: Average weight loss : Most users lose 1520% of body weight within 1218 months