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For instance, a propensity to make an excessively intense innate immune response, or on the contrary the unability to control an infection, the pathogen persistence (potentially due to the previous cause), or a suboptimal functioning of mitochondria, leading to an excess production of reactive oxygen species (ROS), or a suboptimal functioning of the neurovegetative nervous system, facilitating the triggering of dysautonomia, or a propensity do develop autoimmune diseases

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