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Inositol: While its exact mechanism is still under extensive study, inositol is known to be involved in lipid signaling pathways

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Several pathophysiological mechanisms contribute to the onset of these complications, including IR, hyperandrogenism, chronic inflammation, and metabolic abnormalities

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Though resmetirom (a thyroid hormone receptor agonist) is an FDA-approved medication for treatment of MASH with fibrosis, it is not approved for use in pregnancy (77)

The choice between therapies depends on the individual patients clinical profile, including renal function and cardiovascular history. Synjardy Dosing by Renal Function Synjardy dosing by renal function is a critical consideration