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2018, in 169 women under 35 with poor ovarian response, showed CoQ10 pretreatment for 60 days produced significantly higher numbers of retrieved oocytes, higher fertilisation rates, and more high-quality embryos compared to controls

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Cyanocobalamin, or vitamin B12, is sometimes included because it can reduce injection-site discomfort for some patients and may support those who are B12-deficient