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Soula M, Weber RA, Zilka O, Alwaseem H, La K, Yen F, Molina H, Garcia-Bermudez J et al (2020) Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers

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The result is excessive caloric restriction that overwhelms muscle-preservation mechanisms

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Continuous activation of c-Met receptors without recovery periods may lead to receptor internalization and reduced surface expressiona protective mechanism cells employ when signaling pathways are overstimulated

This approach has drawn criticism, especially for stretching the interpretation of patent rights beyond Indias borders, raising concerns about the territorial nature of patents, as discussed here