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Semaglutide: Nausea, diarrhea, and constipation happen here, too, but people may handle it better if they start at a lower dose

This support system fosters accountability and encourages long-term adherence to treatment plans

Walking, climbing stairs, gardening, carrying groceries, playing with children, and household activities all contribute to daily energy expenditure

Sleep disturbances, whether from gastrointestinal discomfort or blood sugar fluctuations, can also contribute to fatigue

Importantly, GLP-1 appears to attenuate reward-driven food consumption by modulating dopaminergic signaling in the mesolimbic system, potentially reducing preference for high-fat, energy-dense foods [36]