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The study results, published in the July 15, 2026, online edition of The Lancet Gastroenterology & Hepatology, address a major unmet need for people with metabolic dysfunctionassociated steatohepatitis (MASH), a serious form of fatty liver disease that can lead to cirrhosis, liver failure, and the need for transplantation

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suggest that GH impacts adipose tissue in a depot-specific manner and impacts other features of adipose tissue (for example, senescence, adipocyte subpopulations, and fibrosis), all of which [may] impact lipolysis