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One KFF analysis estimates that roughly 36 million non-elderly Americans with employer coverage alone meet BMI criteria for a GLP-1, while only a small fraction are taking one today, which points to large latent demand constrained by cost

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This substantial weight reduction correlates with improved cardiovascular outcomes due to decreased obesity-related risk factors

On the short side, companies with concentrated LOE exposure, limited pipeline visibility, and high current multiples relative to post-cliff earnings power are the most exposed

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