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For the first time, this review proposes that COFs have transcended the conventional role of nanocarriers as mere delivery vehicles, thanks to their unparalleled structural orderliness and functional programmability

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Not only does the remethylation of homocysteine contribute to methyl group synthesis, but it also serves as a means to prevent the intracellular accumulation of S-adenosylhomocysteine and an increase in plasma total homocysteine levels [14, 20, 21, 22]

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