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Notably, the Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) trial, the first dedicated kidney outcome trial evaluating canagliflozin in people with type 2 diabetes mellitus and CKD, demonstrated a substantial reduction in the risk of kidney events [46]

The first segment, which would become a recurring feature on The Tonight Show, aired in May 2013 and was a huge success, getting picked up by plenty of blogs and entertainment sites the next day