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These drugs are often talked about as a weight-loss drug, but their bigger promise is in treating obesity, diabetes, and heart disease risk all at once, a cluster of conditions that kills millions of Indians every year

The first week typically marks the beginning of these changes, with the full effect becoming more pronounced in the following weeks

When to Startand When Not To According to the package insert, GLP-1 therapy for obesity is indicated for individuals with a BMI 27 with a weight-related condition, or a BMI 30 alone

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Moderate cardiovascular activity (walking, cycling, swimming) provides important benefits during Retatrutide treatment: Enhanced insulin sensitivity: Aerobic exercise improves glucose uptake and metabolic flexibility Cardiovascular conditioning: Maintains heart health and aerobic capacity during weight loss Mental health benefits: Regular movement reduces anxiety and improves mood, particularly important during medication adjustment phases Additional caloric deficit: Can modestly accelerate fat loss when combined with resistance training Active recovery: Light cardio between resistance sessions promotes blood flow and recovery The key is moderation

Most side effects are gastrointestinal in nature and tend to be most noticeable during the dose escalation phase