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The GIP receptor activation improves fat metabolism, enhances insulin sensitivity in adipose tissue, and provides additional appetite suppression through distinct brain pathways that influence metabolic rate

Russian researchers investigated extracts obtained from organs and tissues, then attempted to identify shorter sequences that might reproduce selected biological effects

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For analysis, 75 l of each supernatant was allocated for mass spectrometry-based thermal protein profiling (TPP), while the remaining 25 l was used for immunoblotting to assess PDE levels