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These preclinical data suggest unimolecular poly-pharmacology as an effective means to target multiple mechanisms contributing to obesity, and further implicate glucagon receptor activation as the differentiating factor between incretin receptor mono- or dual-agonists and triagonists

3.3.2 Arthroscopy Arthroscopic debridement and lavage were historically used in the management of knee OA, especially in the presence of mechanical symptoms such as locking or catching (Medical Advisory Secretariat, 2005)

Effectiveness of physiotherapy for lateral epicondylitis