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Our study is the first to identify a dose-response relationship between vitamin B12 and clinical pregnancy: among women undergoing IVF-ET with the follicular-phase GnRH agonist protocol, clinical pregnancy rates increase with rising serum vitamin B12 levels up to a threshold of approximately 358.7 pg/mL

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Additionally, mutations affecting vitamin B 12 transport and intracellular metabolism have been identified (17)

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