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These modifications include acylation of the peptide backbone with a spacer and a C-18 fatty di-acid chain to lysine at position 26, which mediates strong binding to albumin and potentially results in reduced renal clearance, and an amino-acid substitution in position 8, which results in reduced susceptibility to dipeptidyl peptidase-4 (DPP-4) degradation
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However, long-term effects on growth, bone density, pancreatic health, and thyroid function remain understudied in adolescents
Supplement Facts / Label (may vary product to product): Warnings and Side Effects: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use