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(2009) examined the downstream effects of CJC-1295 DAC-induced GH/IGF-1 axis activation on the serum proteome, identifying changes in proteins related to lipid metabolism, complement activation, and coagulation pathways

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Diabetes Obes Metab 17(9):878886

Finally, it was recently suggested that IGF-I has significant characteristics to be a good marker for the insulin resistance syndrome and risk of cardiovascular disease, since logistic regression analysis showed that each unit increase in log-transformed IGF-I concentrations was associated with a 90.5% reduction in the risk of metabolic syndrome[274]

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