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Preclinical studies demonstrate biologic activity relevant to tissue repair, supporting biologic plausibility but not clinical effectiveness

He indicated a formal FDA announcement could come within weeks of the recording

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The present narrative review is part of a larger project, and we present this companion article that provides a detailed examination of the literature beyond bioactives for estrogen-deficient skin covering the polyphenols (i.e., daidzein, genistein, equol, and resveratrol) [9]