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Methylene Blue Mechanism of Action: Methylene Blue acts on the mitochondria to enhance cellular energy production (ATP), improve cognitive function, and protect the brain from oxidative stress
PMID: 34829776 (view on PubMed) Medical disclaimer This article is for general education and is not a substitute for personalized medical advice, diagnosis, or treatment
LEfSe analysis provided a secondary measure to establish differences between treatment groups in addition to the one-way ANOVA/KruskalWallis tests performed on each genus/phylum
Side Effects & Safety Injection site reactions -- redness, swelling, stinging (common with large-volume SC injections) Flu-like symptoms -- mild fever, fatigue, malaise 24-72 hours post-injection (possibly from immune clearance of apoptotic cells) GI discomfort -- nausea, mild digestive upset Temporary fatigue -- 1-3 days post-injection Off-target cell death (theoretical) -- no compound is perfectly selective
Maier CM, Chan PH
No peer-reviewed study has investigated PDA as a distinct molecule
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