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The potential advantages of advanced signaling by regulated production of H 2 S, for example to coordinate cellular activities for multicellular life, might have demanded both the reversal and repurposing of the transsulfuration pathway

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doi:10.1146/annurev-nutr-120524-043056 Quinn M, Halsey J, Sherliker P, et al

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Although we observed liraglutide-induced overexpression of SST in the -1 subcluster compared with control, gene expression in cells was largely unaffected by liraglutide treatment (Supplemental Figure 4B)