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Body composition changes with retatrutide saw significant decreases in both total and visceral fat while retaining lean muscle mass

To break down the difference between GIP receptors and GLP-1 receptors read below: How GIP receptors work: Increases insulin, aka reduced blood sugar levels Improves fat metabolism and prevents fat storage How GLP-1 receptors work: Enhances fat metabolism Reduces appetite and cravings Lowers blood sugar levels In some cases, cycling/rotating between the two may be beneficial for clients and best results

Libido Changes: Some real patient anecdotal reports mention retatrutide libido changes , citing a lower interest in intimacy

On a molecular level, the drug begins binding to the GLP-1 receptors in your brain and pancreas within hours of your first injection