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10.1001/jamanetworkopen.2023.54734 26 HuangT.YuZ.YuQ.WangY.JiangZ.WangH.et al (2020)
The double-blind multicenter phase 3 trials STEP 1, 3, 4, 5 were conducted in adults (mean age 46.247.3 years), mostly females, with obesity or overweight with 1 weight-related complication (mean BMI 37.838.4 kg/m 2 ) and aimed to demonstrate the superiority of semaglutide 2.4 mg over placebo in BW lowering at 68 or 104 24 weeks as an adjunct to diet and physical activity 23
But, even in its cheaper forms, the cost was a lot to bear
You need the semaglutide vial, an unused insulin syringe (typically 0.5 mL or 1 mL capacity depending on your dose), an alcohol swab, and a sharps disposal container
C., Ohkuma, A., Hayashi, Y
The article says discontinuation studies show weight regain within weeks to months after stopping, and its table calls this rapid regain that requires ongoing therapy
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