The primary objective was to show that orforglipron was non-inferior to oral semaglutide for A1C reduction at 52 weeks
Alcohol enters the bloodstream through the stomach lining, so delayed gastric emptying can extend the time alcohol spends in your digestive tract before absorption
This enhanced metabolic flexibility allows your body to better utilize stored fat for energy and supports sustainable body composition changes
Gastrointestinal Support: Anecdotal relief from ulcers and acid reflux symptoms
To achieve these health benefits, it is critical that people prescribed GLP-1s continue to take them at least long enough to realize clinical success, and preferably longer to avoid possible weight rebound once they come off the medications
The black-box warning focuses on adverse effects (Table 1), while the REMS focuses on specific steps used to lessen these risks, including requiring use of a patient enrollment and monitoring form, a fact sheet for patients, and health care setting and pharmacy enrollment forms
