This theory includes various factors, including lipid accumulation, IR, adipose tissue dysfunction, diet and nutrition, immune responses, changes in the gut microbiome, and genetic and epigenetic factors [21]
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As a result, someone may feel physically full but continue eating during a binge
One consideration unique to covering GLP-1s for anti-obesity is that while plan sponsors will incur new short-term pharmacy costs, expected cost offsets such as lower medical benefit costs may not materialize until years later
