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Common side effects include injection site irritation, mild headache, and transient flushing

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Why Weight Loss Drives Cholesterol Improvement Excess body weight, particularly visceral fat around organs, drives inflammation and metabolic dysfunction that elevates triglycerides and reduces protective HDL cholesterol

Some studies also suggest benefits for non-alcoholic fatty liver disease and obstructive sleep apnea

The first of such dual-agonist, MAR709, shows nearly balanced activity at both target receptors and improves body weight and glycemia with greater potency relative to pharmacokinetically-matched GLP-1 in rodents with diet- and genetically induced obesity (126)

Potential improvement in fertility and menstrual regularity In PCOS, excess weight and insulin resistance disrupt the delicate hormonal balance needed for regular ovulation