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This proximal position of the RAMP2 ECD is conserved in AMY 2 R complexes bound to CT peptides that also have a C-terminal Pro (P32 CT ) (Fig

demonstrate that pitavastatin induces ferroptosis in malondialdehyde (MDA)-MB-231 triple-negative breast cancer cells via mevalonate pathway inhibition, with exogenous mevalonate supplementation partially reversing pitavastatin-induced cytotoxicity and the reduced expression of GPx4/FSP1 (Tang W.-J

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