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Systematic review and meta-analysis of the efficacy of clinically tested protectants of cisplatin nephrotoxicity

It is postulated that ADHD may result from deficits in the dopaminergic system in cortical brain structures such as the prefrontal cortex, subcortical areas such as striatum [54, 55]

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While the first studies showing this were in mice [14], human studies have corroborated these findings [200], although its importance in relationship to traditional clearance pathways across the BBB and subarachnoidal granulations has been challenging to quantify

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