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Selected Essential and Toxic Chemical Elements in Hypothyroidism-A Literature Review (2001-2021)

Apigenin downregulates GLUT1 via inhibition of HIF-1, leading to reduced VEGF secretion and exhibiting both antiproliferative and antimetastatic effects (104)

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40 Hsu CC, Sun CY, Tsai CY, et al

Intestinal barrier dysfunction (leaky gut) permits inappropriate passage of food proteins, microbial components, and environmental toxins into circulation, potentially triggering immune responses that cross-react with body tissues