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urgent medical advice should be sought for severe abdominal pain, persistent vomiting, or visual disturbance

Brain insulin resistance is linked to reduced cholesterol synthesis, which may contribute to Alzheimers disease progression [105]

Phase 3 trials are currently ongoing (see ClinicalTrials.gov for the retatrutide Phase 3 programme), and these larger studies will provide more robust data on the long-term safety and tolerability of retatrutide across more diverse populations

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Reduced efficacy concerns Tirzepatide is primarily prescribed to help manage blood glucose levels in individuals with type 2 diabetes and reduce body weight