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Give semaglutide at least 16 weeks at your target therapeutic dose before concluding that it is insufficient

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Eli Lilly, the company developing it, moved it into Phase 3 after Phase 2 results came back in 2023 showing weight loss numbers that surprised a lot of researchers

The UK SmPC for Wegovy includes a warning about these findings but does not list a history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) as formal contraindications, unlike in some other jurisdictions