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Mapping the interplay of atrial fibrillation, brain structure, and cognitive dysfunction

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However, it is crucial to note that further in-depth and systematic investigation is necessary to elucidate the specific mechanisms underpinning these observations [124]

Further, MTX increased the expression of PERK (Figure 6B), GRP78 (Figure 6C), ATF4 (Figure 6D), and CHOP-10 (Figure 6E) in the liver compared to CTRL, indicating that ER stress is implicated in MTX-induced hepatotoxicity

increases the binding of PAHs to their receptors