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This influential approach laid the foundation for subsequent research on aging

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Dietary shortfall is increasingly common as more clients adopt plant-based eating, because vitamin b12 foods are almost entirely animal-derived: meat, fish, eggs and dairy, with fortified cereals and yeast extracts the main vegan options

Lower doses (600mg) show benefit but with reduced magnitude

Researchers should design protocols with appropriate monitoring, ethical oversight, and realistic safety endpoints

Microglia have a unique immune function in the brain (Tang and Le, 2016) by activating synaptic plasticity