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In this double-blind, placebo-controlled phase 2, trial, 507 adults with obesity (body mass index 30 kg m 2 or 27 kg m 2 with at least one obesity-associated complication (excluding diabetes) were randomized to nine groups (1:1:1:1:1:1:1:1:1 ratio) to receive treatment for 48 weeks: placebo, bimagrumab (10 mg kg 1 or 30 mg kg 1 intravenously every 12 weeks), semaglutide (1.0 mg or 2.4 mg subcutaneously once a week) and combinations thereof

Aloe L, Rocco ML, Balzamino BO, Micera A

In a class action, each class member stands to gain the same resolution, with the exception of the class representatives, who may obtain a different resolution than the class for their additional duties in the litigation

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For women using hormonal contraception, discussing the bleeding pattern with a GP or sexual health specialist may lead to adjustments in contraceptive method or formulation

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