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Availability of data and materials The datasets used and/or analyzed during the current study are available as MS Excel files (.xlsx) and RevMan file (.rm5) from the corresponding author upon reasonable request

Motor : muscle weakness, ataxia, reduced reflexes (if peripheral neuropathy) or increased reflexes and/or upgoing plantars (if central neuropathy)

Pregnancy and Nursing: Nurokind OD Injection is generally considered safe when used to treat a confirmed vitamin B12 deficiency

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Patients with vitamin B12 deficiency and concurrent renal or hepatic disease may require increased doses or more frequent administration of methylcobalamin

This commenter proposed excluding: (1) patients without email or text messaging access, (2) patients who have not given (or have withdrawn) prior consent for text message survey invitations (to comply with the TCPA), and (3) patients who requested confidential admission (to adhere to HIPAA)