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The injectable era is not ending Oral options like orforglipron will not replace injectable GLP-1 medications

Pietrocola et al., 2015)

Neither trajectory is 'better'

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Although Metformin is not FDA-approved for longevity, the agency has authorized its investigation in aging through the TAME (Targeting Aging with Metformin) Triala landmark study exploring its potential to slow age-related decline and extend healthspan