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If youre pregnant or breastfeeding Regulatory bodies, including the MHRA, advise that GLP-1 medications should not be used during pregnancy or while breastfeeding

Lowering blood pressure in the kidney eases the physical force that pushes protein into urine, Cherney says, and by reducing that pressure, it also reduces the mechanical distortion, distension and wall stress on the layers of cells that protect the kidney. This decrease, in turn, lessens the force responsible for fibrosis, a buildup of scar tissue that harms organs

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Overall, 4% (n = 21) of patients had serious events in the intervention group, while 5% (n = 25) were serious in the comparator group

The FDA approved Contrave for use alongside a reduced-calorie diet and increased physical activity