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Thioredoxin (Trx), present in the cytosol as Trx1 and in mitochondria as Trx2, is oxidized and upregulated in response to oxidative stress and elevated ROS levels
International Immunopharmacology, 100(September), 108090
JAMA Intern Med (2013) 173(7):5349
GLP-1 microdosing involves administering low doses of GLP-1 receptor agonists to support preventive health, not just diabetes or rapid weight loss
D.GarrowT
Some anti-inflammatory effects appear independent of weight loss, which is why microdosing is being explored for RA patients who aren't significantly overweight but have signs of metabolic inflammation
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