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QL: Investigation, Writingreview and editing

However, metformin has not been approved as a weight loss drug in part because its effects are highly variable and in women with PCOS despite weight loss visceral fat may not be reduced (21)

Efficacy and Safety of Oral Orforglipron in Patients With Type 2 Diabetes: A Multicentre, Randomised, Dose-Response, Phase 2 Study

Sleeve gastrectomy removes about 80% of the stomach, leaving a narrow tube

Bioavailability is high

Have been out of action for 3 months with awful flu and then an operation, am determined to bounce back with avengence and face this new year with a little verve and vigour