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567 Cationic polymers, such as PLL/PEI, 305,568 have induced cell apoptosis and inflammation in vivo

Epub 2023 May 27

doi:10.6061/clinics/2015(11)09 Bahri Khomami M, Joham AE, Boyle JA, et al

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These variants equally preserved their GSH-transferase activity, suggesting the importance of additional factors in the modulation of the negative log of GSHs acid dissociation constant (p K a ), including the ability to optimally arrange the well-described electron-sharing network which generates a positively charged electrostatic field in the G-site of GSTs 40,41

So far, the peptide has been tested in six randomized controlled trials involving nearly 900 participants, and it has resulted in no serious adverse events