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Immunofluorescence analysis of Caco-2 cells revealed distinct subcellular localizations: MCT4 was exclusively localized to the basolateral plasma membrane, whereas MCT1 exhibited a more uniform distribution, indicating that MCT4 functions as a basolateral efflux transporter [78]

But thats the extent of data we have for the 104 week arm, everything else is 80 week data, so lets look at differences in weight loss in male vs female patients

Maybe they cant afford the drugs

A small proportion of patients (0.9%) switched to ADM tirzepatide

New or worsening neurological symptoms such as paraesthesia or gait disturbance require same-day clinical assessment and prompt parenteral B12 treatment per BSH guidance

Our guide on acute injury definition has more information